Cecilia Frode was educated at Teaterhögskolan i Malmö, Sweden, 1991-1994. She got her breakthrough on stage in Shakespeare´s As you like it 1996 at Göteborgs Stadsteater.

Since then, Cecilia has played many different leading roles on stage in Sweden. Her most recent stage performances took place at the Playhouse Theater, Stockholm, where she portrayed the lead, Rosalind Franklin, in Photograph 51,  Claire in Apologia and Jennie in Gränsfall etc.

She won Guldbaggen, the Swedish equivalent of the Academy Award, for best supporting actress in Klassfesten 2003.

In 2015, Cecilia received the Angela Award for outstanding acting at the European film festival Subtitles in Kilkenny, Ireland for her part in the movie Stockholm Stories.

Cecilia has played supporting and leading roles in feature films such as Sthlm Rekviem, Tårtgeneralen and Stockholm Stories,  and TV-series  like Blå ögon, Coacherna and God morgon alla barn.

The popular Swedish TV-series Mäklarna, where Cecilia plays the female lead Vilma, was a big hit in 2006 and she was nominated for the Golden Nymph at the Monte Carlo tv festival for Outstanding actress-comedy series. The sequel of Mäklarna was streamed in 2021, showing Vilma fifteen years later.

Cecilia Frode has also written, composed music for, and produced teh one-man theater shows Ängelen and En Stjärt på himlen. Both shows went on very successfully tours in Sweden. They were also adapted for broadcast on Swedish national TV.

In 2017, Cecilia Frode wrote and starred in the musical theatre show Från det blå skåpet that went on tour produced for Musik i Syd, Sweden.